Allam, Venkata Sita Rama Raju; Waern, Ida; Taha, Sowsan et. al 2023 Nafamostat has anti-asthmatic effects associated with suppressed pro-inflammatory gene expression, eosinophil infiltration and airway hyperreactivity Research article (Peer reviewed) DOI:10.3389/fimmu.2023.1136780
Akula, Srinivas; Riihimäki, Miia; Waern, Ida et. al 2022 Quantitative Transcriptome Analysis of Purified Equine Mast Cells Identifies a Dominant Mucosal Mast Cell Population with Possible Inflammatory Functions in Airways of Asthmatic Horses Research article (Peer reviewed) DOI:10.3390/ijms232213976
Hellman, Lars; Akula, Srinivas; Fu, Zhirong et. al 2022 Mast Cell and Basophil Granule Proteases-In Vivo Targets and Function Review article (Peer reviewed) DOI:10.3389/fimmu.2022.918305
Akula, Srinivas; Lara, Sandra; Olsson, Anna-Karin et. al 2022 Quantitative Analysis of the Transcriptome of Two Commonly Used Human Monocytic Cell Lines-THP-1 and Mono Mac 6-Reveals Their Arrest during Early Monocyte/Neutrophil Differentiation Research article (Peer reviewed) DOI:10.3390/ijms23105818
Paivandy, Aida; Akula, Srinivas; Lara, Sandra et. al 2022 Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems Research article (Peer reviewed) DOI:10.3390/ijms23031185
Lara, Sandra; Akula, Srinivas; Fu, Zhirong et. al 2022 The Human Monocyte-A Circulating Sensor of Infection and a Potent and Rapid Inducer of Inflammation Research article (Peer reviewed) DOI:10.3390/ijms23073890
Akula, Srinivas; Hellman, Lars; Aviles, Francesc Xavier et. al 2022 Analysis of the mast cell expressed carboxypeptidase A3 and its structural and evolutionary relationship to other vertebrate carboxypeptidases Research article (Peer reviewed) DOI:10.1016/j.dci.2021.104273
Ryu, Jinhye; Fu, Zhirong; Akula, Srinivas et. al 2021 Extended cleavage specificity of a Chinese alligator granzyme B homologue, a strict Glu-ase in contrast to the mammalian Asp-ases Research article (Peer reviewed) DOI:10.1016/j.dci.2021.104324
Fu, Zhirong; Akula, Srinivas; Qiao, Chang et. al 2021 Duodenases are a small subfamily of ruminant intestinal serine proteases that have undergone a remarkable diversification in cleavage specificity Research article (Peer reviewed) DOI:10.1371/journal.pone.0252624
Fu, Zhirong; Akula, Srinivas; Thorpe, Michael et. al 2021 Marked difference in efficiency of the digestive enzymes pepsin, trypsin, chymotrypsin, and pancreatic elastase to cleave tightly folded proteins Research article (Peer reviewed) DOI:10.1515/hsz-2020-0386
Fu, Zhirong; Akula, Srinivas; Olsson, Anna-Karin et. al 2021 Chicken cathepsin G-like - A highly specific serine protease with a peculiar tryptase specificity expressed by chicken thrombocytes Research article (Peer reviewed) DOI:10.1016/j.dci.2021.104337
Fu, Zhirong; Akula, Srinivas; Olsson, Anna-Karin et. al 2021 Mast Cells and Basophils in the Defense against Ectoparasites: Efficient Degradation of Parasite Anticoagulants by the Connective Tissue Mast Cell Chymases Research article (Peer reviewed) DOI:10.3390/ijms222312627
Akula, Srinivas; Fu, Zhirong; Wernersson, Sara et. al 2021 The Evolutionary History of the Chymase Locus -a Locus Encoding Several of the Major Hematopoietic Serine Proteases Review article (Peer reviewed) DOI:10.3390/ijms222010975
Fu, Zhirong; Akula, Srinivas; Thorpe, Michael et. al 2020 Potent and Broad but not Unselective Cleavage of Cytokines and Chemokines by Human Neutrophil Elastase and Proteinase 3 Research article (Peer reviewed) DOI:10.3390/ijms21020651
Teufelberger, Andrea R.; Van Nevel, Sharon; Hulpiau, Paco et. al 2020 Mouse Strain-Dependent Difference Toward the Staphylococcus aureus Allergen Serine Protease-Like Protein D Reveals a Novel Regulator of IL-33 Research article (Peer reviewed) DOI:10.3389/fimmu.2020.582044
Berglund, Petter; Akula, Srinivas; Fu, Zhirong et. al 2020 Extended Cleavage Specificity of the Rat Vascular Chymase, a Potential Blood Pressure Regulating Enzyme Expressed by Rat Vascular Smooth Muscle Cells Research article (Peer reviewed) DOI:10.3390/ijms21228546
Fu, Zhirong; Akula, Srinivas; Thorpe, Michael et. al 2020 Extended Cleavage Specificities of Two Mast Cell Chymase-Related Proteases and One Granzyme B-Like Protease from the Platypus, a Monotreme Research article (Peer reviewed) DOI:10.3390/ijms21010319
Akula, Srinivas; Paivandy, Aida; Fu, Zhirong et. al 2020 How Relevant Are Bone Marrow-Derived Mast Cells (BMMCs) as Models for Tissue Mast Cells? A Comparative Transcriptome Analysis of BMMCs and Peritoneal Mast Cells Research article (Peer reviewed) DOI:10.3390/cells9092118
Grujic, Mirjana; Hellman, Lars; Gustafson, Ann-Marie et. al 2020 Protective role of mouse mast cell tryptase Mcpt6 in melanoma Research article (Peer reviewed) DOI:10.1111/pcmr.12859
Akula, Srinivas; Paivandy, Aida; Fu, Zhirong et. al 2020 Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity Research article (Peer reviewed) DOI:10.3390/cells9010211
Yuan Zhongwei; Akula, Srinivas; Fu, Zhirong et. al 2019 Extended Cleavage Specificities of Rabbit and Guinea Pig Mast Cell Chymases: Two Highly Specific Leu-Ases Research article (Peer reviewed) DOI:10.3390/ijms20246340
Fu, Zhirong; Akula, Srinivas; Thorpe, Michael et. al 2019 Extended cleavage specificity of sheep mast cell protease-2: A classical chymase with preference to aromatic P1 substrate residues Research article (Peer reviewed) DOI:10.1016/j.dci.2018.11.019
Fu, Zhirong; Akula, Srinivas; Thorpe, Michael et. al 2019 Highly Selective Cleavage of TH2-Promoting Cytokines by the Human and the Mouse Mast Cell Tryptases, Indicating a Potent Negative Feedback Loop on TH2 Immunity Research article (Peer reviewed) DOI:10.3390/ijms20205147
Thorpe, Michael; Fu, Zhirong; Albat, Emanuelle et. al 2018 Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5 Research article (Peer reviewed) DOI:10.1371/journal.pone.0207826
Fu, Zhirong; Thorpe, Michael; Akula, Srinivas et. al 2018 Extended Cleavage Specificity of Human Neutrophil Elastase, Human Proteinase 3, and Their Distant Ortholog Clawed Frog PR3-Three Elastases With Similar Primary but Different Extended Specificities and Stability Research article (Peer reviewed) DOI:10.3389/fimmu.2018.02387