Two granzyme A/K homologs in Zebra mbuna have different specificities, one classical tryptase and one with chymase activity
Research article (Peer reviewed)
Sara Wernersson
Department of Anatomy, Physiology and Biochemistry
Faculty of Veterinary Medicine and Animal Sciences
Email: Sara.Wernersson@slu.se
ORCID: 0000-0003-3067-7875
Publications
2023
Extended cleavage specificities of human granzymes A and K, two closely related enzymes with conserved but still poorly defined functions in T and NK cell-mediated immunity
Research article (Peer reviewed)
Nafamostat has anti-asthmatic effects associated with suppressed pro-inflammatory gene expression, eosinophil infiltration and airway hyperreactivity
Research article (Peer reviewed)
2022
Targeting the carboxypeptidase activity: a promising strategy for asthma treatment
Conference abstract
Quantitative Transcriptome Analysis of Purified Equine Mast Cells Identifies a Dominant Mucosal Mast Cell Population with Possible Inflammatory Functions in Airways of Asthmatic Horses
Research article (Peer reviewed)
Treatment of chronic airway diseases using nutraceuticals: Mechanistic insight
Review article (Peer reviewed)
Mast Cell and Basophil Granule Proteases-In Vivo Targets and Function
Review article (Peer reviewed)
Composition and short-term stability of gut microbiota in lean and spontaneously overweight healthy Labrador retriever dogs
Research article (Peer reviewed)
Analysis of the mast cell expressed carboxypeptidase A3 and its structural and evolutionary relationship to other vertebrate carboxypeptidases
Research article (Peer reviewed)
2021
The Evolutionary History of the Chymase Locus -a Locus Encoding Several of the Major Hematopoietic Serine Proteases
Review article (Peer reviewed)