A monoclonal antibody-based sandwich ELISA for measuring canine Thymidine kinase 1 protein and its role as biomarker in canine lymphoma
Research article (Peer reviewed)
Liya Wang
Department of Anatomy, Physiology and Biochemistry
Faculty of Veterinary Medicine and Animal Sciences
Email: Liya.Wang@slu.se
Publications
2023
2022
DTYMK is essential for genome integrity and neuronal survival
Research article (Peer reviewed)
Structural and functional analysis of human thymidylate kinase isoforms
Research article (Peer reviewed)
Differential expression of enzymes in thymidylate biosynthesis in zebrafish at different developmental stages: implications for dtymk mutation-caused neurodegenerative disorders
Research article (Peer reviewed)
Mutational analyses of human thymidine kinase 2 reveal key residues in ATP-Mg2+ binding and catalysis
Research article (Peer reviewed)
Serum TK1 protein and C-reactive protein correlate to treatment response and predict survival in dogs with hematologic malignancies
Research article (Peer reviewed)
Heavy metal tolerance of Mesorhizobium delmotii thymidylate kinase
Research article (Peer reviewed)
2021
Feline thymidine kinase 1: molecular characterization and evaluation of its serum form as a diagnostic biomarker
Research article (Peer reviewed)
Molecular characterization of equine thymidine kinase 1 and preliminary evaluation of its suitability as a serum biomarker for equine lymphoma
Research article (Peer reviewed)
Biochemical Characterizations of Human TMPK Mutations Identified in Patients with Severe Microcephaly: Single Amino Acid Substitutions Impair Dimerization and Abolish Their Catalytic Activity
Research article (Peer reviewed)
Whole-Cell and Mitochondrial dNTP Pool Quantification from Cells and Tissues
Book chapter (Peer reviewed)
2020
Basic biochemical characterization of cytosolic enzymes in thymidine nucleotide synthesis in adult rat tissues: implications for tissue specific mitochondrial DNA depletion and deoxynucleoside-based therapy for TK2-deficiency
Research article (Peer reviewed)
Identification of a novel thymidylate kinase activity
Research article (Peer reviewed)
The expression and activity of thymidine kinase 1 and deoxycytidine kinase are modulated by hydrogen peroxide and nucleoside analogs
Research article (Peer reviewed)
Reply to: Proofreading deficiency in mitochondrial DNA polymerase does not affect total dNTP pools in mouse embryos
Letter (Peer reviewed)
2019
Fibroblast Growth Factor 21 Drives Dynamics of Local and Systemic Stress Responses in Mitochondrial Myopathy with mtDNA Deletions
Research article (Peer reviewed)
Defects in mtDNA replication challenge nuclear genome stability through nucleotide depletion and provide a unifying mechanism for mouse progerias
Research article (Peer reviewed)
DTYMK deficiency is the cause of a novel vanishing brain disease
Conference abstract
2018
Doxorubicin effects on leukemia and breast cancer cells in culture on the TK1 protein levels using AroCell TK 210 ELISA: a tool for drug development
Research article (Peer reviewed)
Quantitative solid-phase assay to measure deoxynucleoside triphosphate pools
Research article (Peer reviewed)
Negative Cooperative Binding of Thymidine, Ordered Substrate Binding, and Product Release of Human Mitochondrial Thymidine Kinase 2 Explain Its Complex Kinetic Properties and Physiological Functions
Research article (Peer reviewed)
2017
mTORC1 regulates mitochondrial integrated stress response and mitochondrial myopathy progression
Research article (Peer reviewed)
Comparison of cellular location and expression of Plakophilin-2 in epidermal cells from nonlesional atopic skin and healthy skin in German shepherd dogs
Research article (Peer reviewed)
2016
MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria
Research article (Peer reviewed)
Mitochondrial purine and pyrimidine metabolism and beyond
Research article (Peer reviewed)
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