Cellular damage triggers mechano-chemical control of cell wall dynamics and patterned cell divisions in plant healing

Abstract

Reactivation of cell division is crucial for the regeneration of damaged tissues, which is a fundamental process across all multicellular organisms. However, the mechanisms underlying the activation of cell division in plants during regeneration remain poorly understood. Here, we show that single-cell endodermal ablation generates a transient change in the local mechanical pressure on neighboring pericycle cells to activate patterned cell division that is crucial for tissue regeneration in Arabidopsis roots. Moreover, we provide strong evidence that this process relies on the phytohormone ethylene. Thus, our results highlight a previously unrecognized role of mechano-chemical control in patterned cell division during regeneration in plants.

Published in

Developmental Cell
2025, volume: 60, number: 10
Publisher: CELL PRESS

SLU Authors

• Di Fino, Luciano

  • Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences
    

• Muhammad Shahzad, Anjam

  • Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences
    

• Mentzelopoulou, Andriani

  • Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences
    
  • University of Crete

• Zahid, Nageena

  • Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences
    

• Ma, Xuemin

  • Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences
    

• Moschou, Panagiotis Nikolaou

  • Department of Molecular Sciences, Swedish University of Agricultural Sciences
    
  • Foundation for Research and Technology - Hellas (FORTH)
  • University of Crete

• Marhavy, Peter

  • Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Developmental Biology
Cell Biology

Publication identifier

• DOI: https://doi.org/10.1016/j.devcel.2024.12.032

Permanent link to this page (URI)

https://res.slu.se/id/publ/142102