Zeppelini, Caio Graco
- Department of Wildlife, Fish and Environmental Studies, Swedish University of Agricultural Sciences
- Federal University of Bahia (UFBA)
Rodent-borne diseases threaten global public health, impacting the urban poor. Despite widespread application of rodenticide in rodent/rodent-borne disease control programs, empirical evidence demonstrating their effectiveness is lacking. This review proposed guidelines for designing and implementing empirical studies on rodenticides as public health measures. The recommendations include: (i) the importance of the type of quasi-experimental design adopted, and how it creates robust evidence; (ii) how urban slums present both challenges for control and ideal settings for studies; (iii) partnering with pest control authorities and community engagement for long-term viability; (iv) leveraging zoonotic systems with direct/environmental transmission, reliable diagnosis, and high prevalence for effectivity assessment; (v) pairing human cohort studies to observe epidemiological links; (vi) systematic data collection and management protocols; (vii) short- and long-term goals for critical evaluation and course-correction; (viii) focus on mechanistic approach; (ix) the need for standardized reporting of the findings.
Rattus; zoonotic disease; public health; research method
Zoonotic diseases
2025, volume: 5, number: 2, article number: 10
Publisher: MDPI
Public Health, Global Health and Social Medicine
https://res.slu.se/id/publ/142979