Magnusson, Ulf
- Department of Obstetrics and Gynaecology, Swedish University of Agricultural Sciences
Abstract
A panel of monoclonal antibodies reacting with different subsets of sheep lymphocytes plus a polyclonal rabbit anti-sheep Ig antiserum were used to characterize threeTheileria hirci-infected lymphoid cell lines that had been infected and transformed in vivo. In parallel, peripheral blood mononuclear cells of Swedish Landrace sheep were exposed to the same antibodies. Whereas the values obtained for healthy Swedish Landrace sheep peripheral mononuclear cells fell within the range previously described for the sheep,T. hirci-infected lymphoid cells reacted only with monoclonal antibodies specific to major histocompatibility (MHC) class I and class H antigens and to leukocyte common antigen (LCA). The results are discussed in the light of the present knowledge on characteristics of bovine lymphoid cells infected and transformed in vivo and in vitro by the related parasitesT. parva andT. annulata. Assumedly, the characteristics of ovine lymphoid cells infected withT. hirci bear likeness to those of bovine cells infected withT. annulata.
Published in
Parasitology Research
1993, volume: 79, number: 3, pages: 195-199
SLU Authors
Uggla, Arvid
- National Veterinary Institute (SVA)
- Sveriges lantbruksuniversitet, Swedish University of Agricultural Sciences
UKÄ Subject classification
Clinical Science
Publication identifier
- DOI: https://doi.org/10.1007/BF00931892
Permanent link to this page (URI)
https://res.slu.se/id/publ/145224