Madej, Andrzej
- Department of Animal Biosciences, Swedish University of Agricultural Sciences
Abstract
Genistein, one of isoflavones, is structurally similar to mammalian endogenous oestrogens, which inhibit activity of tyrosine kinase, DNA topoisomerases, and possess antioxidant activity and oestrogenic activity. The aim of the present work was to study effects of the central administration of genistein on prolactin secretion in ewes during the seasonal anoestrus. The experiment was carried out on twelve Polish Lowland ewes. infusions of genistein into the third ventricle of ewes were performed with calibrated 1.0-ml gas-tight syringes and a microinjection pump. Control infusions (n=4) from 12.01 to 16.01 h were done with a Ringer-Locke solution at flow rate 100 mul/h. The dose of genistein was 1 mug/100 mul/h (n=6) and 10 mug/100 mul/h (n=5) during 4-h infusions. Before the infusions, differences in prolactin concentration between control and experimental animals were insignificant. Prolactin concentrations were significantly (P
Published in
Journal of Animal and Feed Sciences
2004, volume: 13, number: 4, pages: 605-613
Publisher: KIELANOWSKI INST ANIMAL PHYSIOLOGY NUTRITION
SLU Authors
UKÄ Subject classification
Veterinary Science
Animal and Dairy Science
Publication identifier
- DOI: https://doi.org/10.22358/jafs/67628/2004
Permanent link to this page (URI)
https://res.slu.se/id/publ/3134