Sandström, Corine
- Department of Molecular Sciences, Swedish University of Agricultural Sciences
Abstract
The H-1 NMR chemical shifts and NOEs of hydroxy protons in Lewis X trisaccharide, beta-D-Galp-(1 --> 4)[alpha-L-Fucp-(1 -->3) ]-beta-D-GlcpNAc, and Lewis Y tetra sacch aride, alpha-L-Fucp-(1 --> 2)-beta-D-Galp-(1 --> 4)[alpha-L-Fucp-(1 --> 3)]-beta-D-GlcpNAc, were obtained for 85% H2O/15% (CD3)(2)CO solutions. The OH-4 signal of Galp in Lewis X and OH-3, OH-4 signals of Gall), and OH-2 signal of Fucp linked to Galp in Lewis Y had chemical shifts which indicate reduced hydration due to their proximity to the hydrophobic face of the Fucp unit linked to GlcpNAc. The inter-residue NOEs involving the exchangeable NH and OH protons confirmed the stacking interaction between the Fucp linked to the GlcpNAc and the Gall) residues in Lewis X and Lewis Y. (C) 2004 Elsevier Ltd. All rights reserved
Published in
Carbohydrate Research
2004, volume: 339, number: 14, pages: 2465-2468
Publisher: ELSEVIER SCI LTD
SLU Authors
Kenne, Lennart
- Department of Molecular Sciences, Swedish University of Agricultural Sciences
- Department of Molecular Sciences, Swedish University of Agricultural Sciences
UKÄ Subject classification
Organic Chemistry
Publication identifier
- DOI: https://doi.org/10.1016/j.carres.2004.07.002
Permanent link to this page (URI)
https://res.slu.se/id/publ/3144