Schmitz, Monica
- Department of Aquaculture, Swedish University of Agricultural Sciences
Abstract
In the present study a serum-free primary culture of pituitary cells was used to study the direct effect of insulin-like growth factors (IGFs) on gonadotropin gene expression in immature Atlantic salmon. Treatment with IGF I increased the expression of the luteinizing hormone (LH) beta subunit in a dose-dependent manner. IGF I and IGF II had similar potencies, but insulin was less effective in stimulating LH-beta subunit expression. On the other hand, IGFs or insulin had no effect on the expression of the follicle-stimulating hormone (FSH) beta-subunit. The results indicate that the stimulatory effect of IGF I on LH synthesis is exerted through a specific increase of the transcription level of the LH beta subunit
Published in
Fish Physiology and Biochemistry
2003, volume: 28, number: 1-4, pages: 105-106
Publisher: KLUWER ACADEMIC PUBL
SLU Authors
UKÄ Subject classification
Fish and Aquacultural Science
Publication identifier
- DOI: https://doi.org/10.1023/B:FISH.0000030491.40805.96
Permanent link to this page (URI)
https://res.slu.se/id/publ/4285