Intervertebral disc degeneration in the dog. Part 2: Chondrodystrophic and non-chondrodystrophic breeds

Abstract

Dogs can be grouped into two distinct types of breed based on the predisposition to chondrodystrophy, namely, non-chondrodystrophic (NCD) and chondrodystrophic (CD). In addition to a different process of endochondral ossification, NCD and CD breeds have different characteristics of intravertebral disc (IVD) degeneration and IVD degenerative diseases. The anatomy, physiology, histopathology, and biochemical and biomechanical characteristics of the healthy and degenerated IVD are discussed in the first part of this two-part review. This second part describes the similarities and differences in the histopathological and biochemical characteristics of IVD degeneration in CD and NCD canine breeds and discusses relevant aetiological factors of IVD degeneration. (C) 2012 Elsevier Ltd. All rights reserved.

Keywords

Intervertebral disc; Degeneration; Hernia; Dog; Chondrodystrophic; Non-chondrodystrophic; Notochordal cell

Published in

Veterinary Journal
2013, volume: 195, number: 3, pages: 292-299
Publisher: ELSEVIER SCI LTD

SLU Authors

• Bergknut, Niklas

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

• Hagman, Ragnvi

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

• Lagerstedt, Anne-Sofie

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Neurology
Clinical Science
Orthopedics

Publication identifier

• DOI: https://doi.org/10.1016/j.tvjl.2012.10.011

Permanent link to this page (URI)

https://res.slu.se/id/publ/43825