Björkman, Camilla
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
Abstract
The avidity (functional affinity) of specific antibodies are being used to estimate duration of bovine Neospora caninum infection. Here, we report for the first time the avidity pattern in cattle orally inoculated with N. caninum oocysts. In all, 16 pregnant cows and 7 calves were administered N. caninum oocysts. In the cows, the avidity increased during the early course of infection. In all but one, the avidity was 50 until week 9. The calves were sampled either week 6 (n = 3) or week 9 (n = 9) after infection, and by then had avidities between 2 and 17. The results are in agreement with results from previous investigations of naturally infected cattle, and calves that were experimentally infected with tachyzoites. They further validate the ability of the N. caninum iscom avidity ELISA to accurately assess the duration of infection. (c) 2004 Elsevier B.V. All rights reserved
Published in
Veterinary Parasitology
2005, volume: 128, number: 3-4, pages: 195-200
Publisher: ELSEVIER SCIENCE BV
SLU Authors
UKÄ Subject classification
Clinical Science
Publication identifier
- DOI: https://doi.org/10.1016/j.vetpar.2004.11.030
Permanent link to this page (URI)
https://res.slu.se/id/publ/4456