Patients with anaemia can shift from kidney to liver production of erythropoietin as shown by glycoform analysis

Lönnberg, Maria; Garle, Mats; Lönnberg, Lina; Birgegård, Gunnar

doi:10.1016/j.jpba.2013.04.009

Abstract

This glycoform analysis has made it possible to affirm that some anaemic patients can increase their liver-production of EPO. The use of such a method can give better insight into the regulation of non-renal endogenous EPO production, a potential source of EPO intended to replace administration of exogenous EPO. (C) 2013 Elsevier B.V. All rights reserved.

Keywords

EPO; Epoetin; Darbepoetin; Haemodialysis; Lectin chromatography; WGA

Published in

Journal of Pharmaceutical and Biomedical Analysis
2013, volume: 81-82, pages: 187-192
Publisher: ELSEVIER SCIENCE BV

SLU Authors

Lönnberg, Lina
- Department of Ecology, Swedish University of Agricultural Sciences

UKÄ Subject classification

Analytical Chemistry

Publication identifier

DOI: https://doi.org/10.1016/j.jpba.2013.04.009

Permanent link to this page (URI)

https://res.slu.se/id/publ/56192