Fine mapping and replication of QTL in outbred chicken advanced intercross lines

Abstract

Conclusions: Our results indicate that many of the QTL, which are genome-wide significant or suggestive in the analyses of large intercross populations, are true effects that can be replicated and fine-mapped using AIL. Key factors for success are the use of large populations and powerful statistical tools. Moreover, we believe that the statistical methods we have developed to efficiently study outbred AIL populations will increase the number of organisms for which in-depth complex traits can be analyzed.

Published in

Genetics Selection Evolution
2011, volume: 43
Publisher: BIOMED CENTRAL LTD

SLU Authors

• Besnier, Francois

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Rönnegård, Lars

  • Dalarna University

• Ek, Weronica

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Andersson, Leif

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    
  • Uppsala University

• Carlborg, Örjan

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    
  • Uppsala University

UKÄ Subject classification

Animal and Dairy Science
Veterinary Science

Publication identifier

• DOI: https://doi.org/10.1186/1297-9686-43-3

Permanent link to this page (URI)

https://res.slu.se/id/publ/57696