Integration of growth and patterning during vascular tissue formation in Arabidopsis

Abstract

Coordination of cell division and pattern formation is central to tissue and organ development, particularly in plants where walls prevent cell migration. Auxin and cytokinin are both critical for division and patterning, but it is unknown how these hormones converge upon tissue development. We identify a genetic network that reinforces an early embryonic bias in auxin distribution to create a local, nonresponding cytokinin source within the root vascular tissue. Experimental and theoretical evidence shows that these cells act as a tissue organizer by positioning the domain of oriented cell divisions. We further demonstrate that the auxin-cytokinin interaction acts as a spatial incoherent feed-forward loop, which is essential to generate distinct hormonal response zones, thus establishing a stable pattern within a growing vascular tissue.

Published in

Science
2014, volume: 345, number: 6197, article number: 1255215
Publisher: AMER ASSOC ADVANCEMENT SCIENCE

SLU Authors

• Novak, Ondrej

  • Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences
    
  • Palacký University Olomouc

• Ljung, Karin

  • Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Botany
Cell and Molecular Biology

Publication identifier

• DOI: https://doi.org/10.1126/science.1255215

Permanent link to this page (URI)

https://res.slu.se/id/publ/67883