Pettersson, Hans
- Department of Applied Animal Science and Welfare, Swedish University of Agricultural Sciences
Abstract
The ability of human gastrointestinal organisms to transform the trichothecenes 3-acetyldeoxynivalenol and nivalenol was investigated. Samples of human faeces were incubated under anaerobic conditions for 48 h with the toxins. They were then extracted and analysed for trichothecenes and metabolites. 3-Acetyldeoxynivalenol was metabolized to deoxynivalenol during the incubation period. In contrast to what has been reported for other species such as rats, mice and pigs, no de-epoxidated metabolites were detected in the faecal incubates. The toxicological significance of the difference in the intestinal ability to transform trichothecenes between species is unknown
Keywords
deoxynivalenol; nivalenol; metabolism; de-epoxidation; gastrointestinal; humans; faeces
Published in
Food Additives And Contaminants
2003, volume: 20, number: 6, pages: 579-582
Publisher: TAYLOR & FRANCIS LTD
SLU Authors
UKÄ Subject classification
Food Science
Publication identifier
- DOI: https://doi.org/10.1080/0265203031000102573
Permanent link to this page (URI)
https://res.slu.se/id/publ/768