Eklund, Hans
- Department of Molecular Biology, Swedish University of Agricultural Sciences
Abstract
In this report we describe the main features of the initially determined alcohol dehydrogenase, that of horse liver, relate this to the human enzyme structures and review recent structural studies on mutants and new complexes of the enzymes. We further review the structure of a bacterial alcohol dehydrogenase to arrive at a coherent picture of medium-chain dehydrogenase/reductase alcohol dehydrogenases in general.
Keywords
Crystal structures; dimeric ADH; tetrameric ADH; zinc; NADH
Published in
Cellular and Molecular Life Sciences
2008, volume: 65, number: 24, pages: 3907-3917
Publisher: BIRKHAUSER VERLAG AG
SLU Authors
UKÄ Subject classification
Cell Biology
Publication identifier
- DOI: https://doi.org/10.1007/s00018-008-8589-x
Permanent link to this page (URI)
https://res.slu.se/id/publ/77794