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Abstract

Individual mid-lactation milk samples were collected from 116 cows of the Swedish Red and Swedish Holstein breeds with known genotypes of beta-casein, kappa-casein and beta-lactoglobulin. Detailed milk protein composition and allele-specific expression of beta-casein, kappa-casein and beta-lactoglobulin proteins in milk were analysed using reversed-phase high-performance liquid chromatography. Aggregate beta-/kappa-casein genotype was significantly associated with the kappa-casein concentration in milk. The lowest kappa-casein concentration was found in milk of cows with genotypes including kappa-casein E (A(1)A(2)/AE, A(1)A(1)/AE) and also A(2)A(2)/AA milk, whereas highest levels were associated with genotypes including kappa-casein B. Casein number was positively and concentration of beta-lactoglobulin negatively associated with the beta-lactoglobulin BB genotype. In heterozygote cows, beta-casein A(1) and beta-lactoglobulin A proteins were found at higher concentrations in milk compared with the protein variant encoded by the alternative allele at these loci, whereas kappa-casein A and B variants were found at similar concentrations in heterozygote AB cows.

Keywords

genetic polymorphism; milk protein expression; milk protein composition; RP-HPLC

Published in

Journal of Animal Breeding and Genetics
2008, volume: 125, number: 2, pages: 119-129
Publisher: WILEY-BLACKWELL

SLU Authors

UKÄ Subject classification

Animal and Dairy Science
Food Science

Publication identifier

  • DOI: https://doi.org/10.1111/j.1439-0388.2007.00706.x

Permanent link to this page (URI)

https://res.slu.se/id/publ/78172