Differential Retinoic Acid Signaling in Tumors of Long-and Short-term Glioblastoma Survivors

Barbus, Sebastian; Tews, Bjoern; Karra, Daniela; Hahn, Meinhard; Radlwimmer, Bernhard; Delhomme, Nicolas; Hartmann, Christian; Felsberg, Joerg; Krex, Dietmar; Schackert, Gabriele; Martinez, Ramon; Reifenberger, Guido; Lichter, Peter

doi:10.1093/jnci/djr036

Research article2011Peer reviewedOpen access

Differential Retinoic Acid Signaling in Tumors of Long-and Short-term Glioblastoma Survivors

Barbus, Sebastian; Tews, Bjoern; Karra, Daniela; Hahn, Meinhard; Radlwimmer, Bernhard; Delhomme, Nicolas; Hartmann, Christian; Felsberg, Joerg; Krex, Dietmar; Schackert, Gabriele; Martinez, Ramon; Reifenberger, Guido; Lichter, Peter

Abstract

Although the prognosis of most glioblastoma patients is poor, 3%-5% patients show long-term survival of 36 months or longer after diagnosis. To study the differences in activation of biochemical pathways, we performed mRNA and protein expression analyses of primary glioblastoma tissues from 11 long-term survivors (LTS; overall survival >= 36 months) and 12 short-term survivors (STS; overall survival

Published in

JNCI: Journal of the National Cancer Institute
2011, volume: 103, number: 7, pages: 598-601
Publisher: OXFORD UNIV PRESS INC

SLU Authors

Delhomme, Nicolas
- German Cancer Research Center

UKÄ Subject classification

Genetics and Genomics
Bioinformatics and Computational Biology (Methods development to be 10203)

Publication identifier

DOI: https://doi.org/10.1093/jnci/djr036

Permanent link to this page (URI)

https://res.slu.se/id/publ/80798