Pohanka, Anton
- Department of Molecular Sciences, Swedish University of Agricultural Sciences
Abstract
Four dialkylresorcinols (1-4) were isolated from a liquid culture of Pseudomonas sp. Ki19. Compounds 1 and 2, 2-butyl-5-propylresorcinol and 2-hexyl-5-methylresorcinol, respectively, have not previously been isolated from biological sources, whereas 3 and 4, 2-hexyl-5-propylresorcinol (DB-2073) and 2-hexyl-5-pentylresorcinol ( resorstatin), both have been found in biological systems. The compounds inhibited Staphyllococcus aureus at concentrations <= 10 mu g/mL as well as the fungi Aspergillus fumigatus and Fusarium culmorum at 50 mu g/mL. The formation of possible antimicrobial quinone oxidation products was investigated under bioassay conditions, and they were not found to be responsible for the main antimicrobial activity.
Published in
Journal of Natural Products
2006, volume: 69, number: 4, pages: 654-657
Publisher: AMER CHEMICAL SOC
SLU Authors
Broberg, Anders
- Department of Molecular Sciences, Swedish University of Agricultural Sciences
- Department of Molecular Sciences, Swedish University of Agricultural Sciences
UKÄ Subject classification
Microbiology
Publication identifier
- DOI: https://doi.org/10.1021/np0600595
Permanent link to this page (URI)
https://res.slu.se/id/publ/8647