Kushwaha, Nirbhay
- Department of Plant Biology, Swedish University of Agricultural Sciences
Review article2019Peer reviewedOpen access
Kushwaha, Nirbhay Kumar; Hafren, Anders; Hofius, Daniel
Autophagy is a conserved self-cleaning and renewal system required for cellular homeostasis and stress tolerance. Autophagic processes are also implicated in the response to 'non-self' such as viral pathogens, yet the functions and mechanisms of autophagy during plant virus infection have only recently started to be revealed. Compelling evidence now indicates that autophagy is an integral part of antiviral immunity in plants. It can promote the hypersensitive cell death response upon incompatible viral infections or mediate the selective elimination of entire particles and individual proteins from compatible viruses in a pathway similar to xenophagy in animals. Several viruses, however, have evolved measures to antagonize xenophagic degradation or utilize autophagy to suppress disease-associated cell death and other defence pathways like RNA silencing. Here, we highlight the current advances and gaps in our understanding of the complex autophagy-virus interplay and its consequences for host immunity and viral pathogenesis in plants.
ATG8; autophagy; innate immunity; plants; selective cargo receptor; virus; xenophagy
Molecular Plant Pathology
2019, Volume: 20, number: 9, pages: 1211-1216 Publisher: WILEY
SLU Plant Protection Network
Biochemistry and Molecular Biology
DOI: https://doi.org/10.1111/mpp.12852
https://res.slu.se/id/publ/101385