Strömstedt, Lina
- Department of Animal Biosciences, Swedish University of Agricultural Sciences
Research article2006Peer reviewed
Epistasis and the release of genetic variation during long-term selection
Carlborg O, Jacobsson L, Ahgren P, Siegel P, Andersson L
Abstract
It is an enigma how long-term selection in model organisms and agricultural species can lead to marked phenotypic changes without exhausting genetic variation for the selected trait. Here, we show that the genetic architecture of an apparently major locus for growth in chicken dissects into a genetic network of four interacting loci. The interactions in this radial network mediate a considerably larger selection response than predicted by a single-locus model
Published in
Nature Genetics
2006, Volume: 38, number: 4, pages: 418-420
Publisher: NATURE PUBLISHING GROUP
Andersson, Leif
- Department of Animal Biosciences, Swedish University of Agricultural Sciences
- Department of Animal Biosciences, Swedish University of Agricultural Sciences
Carlborg, Örjan
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
- Department of Clinical Sciences, Swedish University of Agricultural Sciences
SLU Authors
UKÄ Subject classification
Animal and Dairy Science
Veterinary Science
Publication identifier
DOI: https://doi.org/10.1038/ng1761
Permanent link to this page (URI)
https://res.slu.se/id/publ/10481