Lessons, insights and newly developed tools emerging from behavioral phenotyping core facilities

Abstract

Scientific investigations, in general, and research in neuroscience, in particular, are becoming ever more complex and require the integration of different techniques. Behavioral assays, which are among the most frequently used methodologies in neuroscience, nowadays rely on advanced, sophisticated technologies that require proficient application. Therefore, behavioral core facilities are becoming essential support units, as they provide the specialized expert research services needed to conduct advanced neuroscience. We here review the lessons learned and insights gathered from managing behavioral core facilities in different academic research institutes. This review addresses several issues, including: the advantages of behavioral core facilities, considerations for establishing a behavioral core facility, and the methodological advances made through calibration and standardization of assay protocols and the development of new assays. Collectively, the review highlights the benefits of both working within and collaborating with behavioral core facility units and emphasizes the potential progress in neuro-phenotyping that such facilities provide.

Keywords

Behavioral core facilities; Calibration; New assays development; Mice; Zebra fish

Published in

Journal of Neuroscience Methods
2020, Volume: 334, article number: 108597Publisher: ELSEVIER

SLU Authors

• Roman, Erika

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    
  • Uppsala University

UKÄ Subject classification

Behavioral Sciences Biology


Publication identifier

DOI: https://doi.org/10.1016/j.jneumeth.2020.108597

Permanent link to this page (URI)

https://res.slu.se/id/publ/105386