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Research article - Peer-reviewed, 1998

Temporary suppression of cell-mediated immunity in Standardbred horses with decreased athletic capacity

Jensen-Waern, M; Persson, SGB; Nordengrahn, A; Merza, M; Fossum, C


Eighty Standardbred horses, originating from 5 training campuses, with decreased athletic performance in association with symptoms such as intermittent fever and mild pharyngitis were examined. As control animals, 10 horses from a stable with normally performing horses were used. Virus isolation and clinico-chemical and serological tests were performed. Lymphocyte proliferation tests were carried out to evaluate the capacity of the cell-mediated immunity. In addition, a bioassay for equine type I interferon, as a marker for early viral infections, was established. No specific microbe could be linked to these symptoms, but there was a temporary suppression of the cell-mediated immunity, which might be explained by the serological evidence of an EHV-2 and/or rhinovirus infection.


poor performance; lymphocyte proliferation; equine interferon; virus; serology

Published in

Acta Veterinaria Scandinavica
1998, Volume: 39, number: 1, pages: 25-33

      SLU Authors

      • Fossum, Caroline

        • Department of Veterinary Microbiology, Swedish University of Agricultural Sciences

      UKÄ Subject classification


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