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Research article - Peer-reviewed, 2020

Left ventricular M-mode prediction intervals in 7651 dogs: Population-wide and selected breed-specific values

Esser, Lilith Carla; Borkovec, Martin; Bauer, Alexander; Haggstrom, Jens; Wess, Gerhard


Background: Echocardiography is a common method to measure heart size in dogs. The heart dimensions are influenced by body weight (BW) and potentially by breed.Objectives: To establish BW-dependent prediction intervals (PIs) of the left ventricular (LV) linear dimensions in a population of dogs of many breeds in multicenter environment, and to identify breeds deviating from these intervals.Dogs: Seven thousand six hundred and fifty-one dogs.Methods: Retrospectively, data from heart screens conducted between 2009 and 2016 were included. Cardiac dimensional PIs were generated using allometric scaling including all nonsighthound dogs and values were compared to previously published PIs. The values measured in dogs of respective breeds, including sighthounds, were then compared to the overall nonsighthound PIs to identify deviant breeds. The interobserver-variability of the measurements was determined using the explained residual variance.Results: Prediction intervals for the nonsighthound dogs were in agreement with previously published cardiac PIs, although the upper limits of the generated PIs of our study were slightly below those currently applied (except the interventricular septum in systole and the left ventricular free wall in diastole below 10.0 kg and 15.0 kg, respectively). Values measured in the nonsighthound breed Newfoundland deviated for most dimensions. Most of the sighthound breeds analyzed had greater cardiac dimensions, with the exception of the Irish Wolfhound.Conclusion and Importance: Findings of our study reinforces the value of BW-dependent PIs for cardiac dimensions in dogs and suggest that these PIs are valid for most nonsighthound breeds, but not the sighthound breeds.


body weight; canine; echocardiography; heart dimensions; prediction intervals

Published in

Journal of Veterinary Internal Medicine
2020, Volume: 34, number: 6, pages: 2242-2252
Publisher: WILEY

    UKÄ Subject classification

    Clinical Science

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