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Research article2006Peer reviewedOpen access

Association of canine hypothyroidism with a common major histocompatibility complex DLA class II allele

Kennedy, LJ; Quarmby, S; Happ, GM; Barnes, A; Ramsey, IK; Dixon, RM; Catchpole, B; Rusbridge, C; Graham, PA; Hillbertz, NS; Roethel, C; Dodds, WJ; Carmichael, NG; Ollier, WER

Abstract

Dogs exhibit a range of immune-mediated conditions including a lymphocytic thyroiditis which has many similarities to Hashimoto's thyroiditis in man. We have recently reported an association in Doberman Pinschers between canine hypothyroidism and a rare DLA class II haplotype that contains the DLA-DQA1*00101 allele. We now report a further series of 173 hypothyroid dogs in a range of breeds where a significant association with DLA-DQA1*00101 is shown

Published in

Tissue Antigens
2006, volume: 68, number: 1, pages: 82-86
Publisher: BLACKWELL PUBLISHING

SLU Authors

UKÄ Subject classification

Veterinary Science
Animal and Dairy Science

Publication identifier

  • DOI: https://doi.org/10.1111/j.1399-0039.2006.00614.x

Permanent link to this page (URI)

https://res.slu.se/id/publ/10936