DMPU: An Alternative to HMPT in Moth Sex Pheromone Synthesis

Abstract

1,3-Dimethyl-2-oxo-hexahydropyrimidine (DMPU, or N,N′-dimethylpropyleneurea) is found to be a good substitute for the carcinogenic hexamethylphosphoric triamide (HMPT) as cosolvent in the alkylation of lithium 1-alkynides, key intermediates in moth sex pheromone synthesis.

Published in

Synthesis
1988, number: 3, pages: 250-252

UKÄ Subject classification

Organic Chemistry


Publication identifier

DOI: https://doi.org/10.1055/s-1988-27534

Permanent link to this page (URI)

https://res.slu.se/id/publ/110605