Research article - Peer-reviewed, 2020
Self-Assembly of Asymmetrically Functionalized Titania Nanoparticles into Nanoshells
Svensson, Fredric G.; Seisenbaeva, Gulaim A.; Kotov, Nicholas A.; Kessler, Vadim G.Abstract
Titania (anatase) nanoparticles were anisotropically functionalized in water-toluene Pickering emulsions to self-assemble into nanoshells with diameters from 500 nm to 3 mu m as candidates for encapsulation of drugs and other compounds. The water-phase contained a hydrophilic ligand, glucose-6-phosphate, while the toluene-phase contained a hydrophobic ligand, n-dodecylphosphonic acid. The addition of a dilute sodium alginate suspension that provided electrostatic charge was essential for the self-limited assembly of the nanoshells. The self-assembled spheres were characterized by scanning electron microscopy, elemental mapping, and atomic force microscopy. Drug release studies using tetracycline suggest a rapid release dominated by surface desorption.Keywords
self-assembly; nanoshells (hollow spheres); janus particles; pickering emulsionPublished in
Materials2020, volume: 13, number: 21, article number: 4856
Publisher: MDPI
Authors' information
Svensson, Fredric
Swedish University of Agricultural Sciences, Department of Molecular Sciences
Swedish University of Agricultural Sciences, Department of Molecular Sciences
Kotov, Nicholas
Swedish University of Agricultural Sciences, Department of Molecular Sciences
Swedish University of Agricultural Sciences, Department of Molecular Sciences
UKÄ Subject classification
Nano-technology
Publication Identifiers
DOI: https://doi.org/10.3390/ma13214856
URI (permanent link to this page)
https://res.slu.se/id/publ/112373