Research article - Peer-reviewed, 2021
AA amyloid in human food chain is a possible biohazardRising, Anna; Gherardi, Paola; Chen, Gefei; Johansson, Jan; Oskarsson, Marie E.; Westermark, Gunilla T.; Westermark, Per
AbstractAA amyloidosis can be transmitted experimentally in several mammalian and avian species as well as spontaneously between captive animals, even by oral intake of amyloid seeds. Amyloid seeding can cross species boundaries, and fibrils of one kind of amyloid protein may also seed other types. Here we show that meat from Swedish and Italian cattle for consumption by humans often contains AA amyloid and that bovine AA fibrils efficiently cross-seed human amyloid beta peptide, associated with Alzheimer's disease.
Published inScientific Reports
2021, volume: 11, number: 1, article number: 21069
Publisher: NATURE PORTFOLIO
Swedish University of Agricultural Sciences, Department of Anatomy, Physiology and Biochemistry (AFB)
Azienda Unità Sanitaria Locale Di Piacenza
Oskarsson, Marie E.
Westermark, Gunilla T.
UKÄ Subject classification
Biochemistry and Molecular Biology
URI (permanent link to this page)