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Review article - Peer-reviewed, 2022

Vaccination of Immunocompromised Cats

Hartmann, Katrin; Moestl, Karin; Lloret, Albert; Thiry, Etienne; Addie, Diane D.; Belak, Sandor; Boucraut-Baralon, Corine; Egberink, Herman; Frymus, Tadeusz; Hofmann-Lehmann, Regina; Lutz, Hans; Marsilio, Fulvio; Pennisi, Maria Grazia; Tasker, Severine; Truyen, Uwe; Hosie, Margaret J.


Immunocompromise is a common condition in cats, especially due to widespread infections with immunosuppressive viruses, such as feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV), but also due to chronic non-infectious diseases, such as tumours, diabetes mellitus, and chronic kidney disease, as well as treatment with immunosuppressive drugs, such as glucocorticoids, cyclosporins, or tumour chemotherapy. In this review, the European Advisory Board on Cat Diseases (ABCD), a scientifically independent board of experts in feline medicine from eleven European countries, discusses the current knowledge and rationale for vaccination of immunocompromised cats. So far, there are few data available on vaccination of immunocompromised cats, and sometimes studies produce controversial results. Thus, this guideline summarizes the available scientific studies and fills in the gaps with expert opinion, where scientific studies are missing. Ultimately, this review aims to help veterinarians with their decision-making in how best to vaccinate immunocompromised cats.


feline; immunocompromise; immunosuppression; immunodeficiency; vaccine; efficacy; safety; duration of immunity; DOI

Published in

2022, volume: 14, number: 5, article number: 923
Publisher: MDPI

Authors' information

Hartmann, Katrin
University of Munich
Moestl, Karin
University of Veterinary Medicine Vienna
Lloret, Albert
Autonomous University of Barcelona
Thiry, Etienne
University of Liege
Addie, Diane D.
University of Glasgow
Belák, Sándor (Belak, Sandor)
Swedish University of Agricultural Sciences, Department of Biomedical Science and Veterinary Public Health
Egberink, Herman
Utrecht University
Frymus, Tadeusz
Warsaw University of Life Sciences
Hofmann-Lehmann, Regina
University of Zurich
Lutz, Hans
University of Zurich
Marsilio, Fulvio
University of Teramo
Pennisi, Maria Grazia
University of Messina
Tasker, Severine
University of Bristol
Tasker, Severine
Linnaeus Vet Ltd
Truyen, Uwe
Leipzig University
Hosie, Margaret J.
University of Glasgow

UKÄ Subject classification

Clinical Science

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