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Research article - Peer-reviewed, 2023

Concentrating and sequestering biomolecules in condensates: impact on plant biology

Mountourakis, Fanourios; Hatzianestis, Ioannis H.; Stavridou, Stella; Bozhkov, Peter, V; Moschou, Panagiotis N.


Biomolecules can exist in a variety of forms, ranging from single entities to mesoscale assemblies akin to small organelles, also known as ‘biomolecular condensates’. The formation of biomolecular condensates is expedited by phase separation, in which molecules de-mix to form dilute and condensed phases. Phase separation results in concentrating or sequestering certain molecules, thus altering their abundance or other features in the phases and in this way inhibiting or promoting biochemical reactions. Here, we discuss recent research implicating biomolecular condensates in the regulation of biochemical reactions in plants.


Enzyme regulation; phase separation; protein condensation; signaling

Published in

Journal of Experimental Botany
2023, Volume: 74, number: 5, pages: 1303-1308