Sandström, Corine
- Department of Molecular Sciences, Swedish University of Agricultural Sciences
Research article2023Peer reviewedOpen access
On the reactivity of 2-methylene-3-quinuclidinone in water
Ringom, Rune; Blizzard, Tim; Sandström, Corine; Svensson, Per H.; Hagberg, Lars
Abstract
The biologically active Michael acceptor 2-methylene-3-quinuclidinone (MQ) has a unique chemical reactivity and forms several products upon dissolution in water. With the use of X-ray, NMR and LCMS data the structures of two previously incorrectly characterised compounds are rectified. A complex equilibrium in water, containing novel dimeric species of MQ, and its dependence on temperature, pH and concentration is presented.
Published in
Heterocycles
2023, Volume: 106, number: 2, pages: 271-276
SLU Authors
UKÄ Subject classification
Organic Chemistry
Publication identifier
DOI: https://doi.org/10.3987/COM-22-14797
Permanent link to this page (URI)
https://res.slu.se/id/publ/123432