Roos, Stefan
- Department of Molecular Sciences, Swedish University of Agricultural Sciences
Patent2023
Use of inosine for the treatment of t-reg deficiency
Roos, Stefan; Liu, Yuying; He, Baokun; Rhoads, Jon Marc
Abstract
The present invention provides the use of inosine in the treatment of a disease associated with Treg deficiency or Treg dysfunction, in particular immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX). In one embodiment of the invention, the inosine can be provided in the form of a bacterial strain that is capable of stimulating the production of inosine. Methods for stimulating the production of inosine in a subject using said strains are also provided, as are methods for the selection of a bacterial strain capable of stimulating inosine production in a subject.
Published in
Application number: US16/304,747
Patent number: US11602551B2
Application published date: 2021-03-04
Publication date: 2023-03-14
SLU Authors
UKÄ Subject classification
Microbiology in the medical area
More information
Assignees: Biogaia AB and Board of Regents of the University of Texas System
Permanent link to this page (URI)
https://res.slu.se/id/publ/126735