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Research article2006Peer reviewed

Transient expression of a major ampullate spidroin 1 gene fragment from Euprosthenops sp. in mammalian cells

Grip, S; Rising, A; Nimmervoll, H; Storckenfeldt, E; Mcqueen-Mason, SJ; Pouchkina-Stantcheva, N; Vollrath, F; Engström, W; Fernandez-Arias, A

Abstract

Spider silk possesses extraordinary and unsurpassed mechancal properties and several attempts have been made to artificialy produce spider sild in order to manufacture strong and light engineering composites. In the field of oncology, recombinant spider sild has the potential to be used as a biomaterial for bone replacement after tumour surgery. In this study, a 636-base pair gene fragment, coding for a part of Major Ampullate silk protein 1 from the African spider, Euprosthenops sp., was cloned into the expressino vector pSecTag2/Hygro A, designed fro the production of protein in mammalian cells

Published in

Cancer Genomics and Proteomics
2006, Volume: 3, number: 2, pages: 83-88