Seroprevalence of Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum in dogs with neurological signs

Abstract

A retrospective cohort study was carried out to evaluate whether seropositivity for the tick-transmitted bacterial species Borrelia burgdorferi sensu lato and/or Anaplasma phagocytophilum was associated with one or more specific categories of nervous system disorders in dogs. A total of 248 dogs with nervous system disorders were serotested for these agents and categorised into six main diagnostic categories: degenerative diseases of the spine, epilepsy, inflammatory diseases, neoplasia, peripheral neuropathies, and other diseases. Multivariable analysis using logistic regression was used to model whether a dog was diagnosed as being in any of these categories. The independent variables included were sex, age, year of serological testing, and whether the animal tested positive for B burgdorferi sensu lato and/or A phagocytophilum. in one model, a statistically significant association was found between a positive titre for A phagocytophilum and the risk of a dog developing neoplastic disease. Although statistically significant, it was concluded that the association was not of clinical relevance

Published in

Veterinary Record
2007, volume: 160, number: 24, pages: 825-831
Publisher: BRITISH VETERINARY ASSOC

SLU Authors

• Hultin Jäderlund, Karin

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

• Egenvall, Agneta

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

• Hedhammar, Åke

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Veterinary Science
Animal and Dairy Science

Publication identifier

• DOI: https://doi.org/10.1136/vr.160.24.825

Permanent link to this page (URI)

https://res.slu.se/id/publ/15923