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Research article2003Peer reviewed

Pharmacokinetics and pharmacodynamics of clemastine

Pettersson, K; Bergvall, K; Hedeland, M; Bondesson, U; Broström, H; Törneke, K; Ingvast-Larsson, C

Abstract

Clemastine is an H1 antagonist used in certain allergic disorders in humans and tentatively also inhorses,although the pharmacology of thedrug in this species has not yet been investigated. In the present stydy we determined basic pharmacokinetic parameters and compard the effect of the drug measured as inhibition of histamine-induced cutaneous wheal formation in six horses

Keywords

clemastine; horse

Published in

Journal of Veterinary Pharmacology and Therapeutics
2003, Volume: 26, pages: 151-157
Publisher: Blackwell Publishing Ltd