Research article - Peer-reviewed, 2008
Verrucine F, a quinazoline from Penicillium verrucosum
Leong SI, Schnurer J, Broberg AAbstract
Verrucine F (3), a quinazoline similar to verrucines A (1) and B (2), contains one anthranilic acid residue, one L-glutamine residue, and one alpha,beta-unsaturated phenylalanine residue, as determined by NMR, MS, and chemical methods. Compounds I and 3, but not 2, were produced by Penicillium verrucosum J255 and eight additional P. verrucosum strains. Verrucines were typically more concentrated in the inner (older) parts of the colony, and 3 peaked 4-8 days after 1, but at 10-fold lower concentrations (similar to 200 mu g/g). Verrucine F (3) formed spontaneously from 1 in buffered water solutions. probably by oxidation at C-1 followed by water eliminationPublished in
Journal of Natural Products2008, volume: 71, number: 8, pages: 1455-1457
Publisher: AMER CHEMICAL SOC
Authors' information
Leong, Su-Lin (Hedén, Su-Lin)
Swedish University of Agricultural Sciences, Department of Microbiology
Swedish University of Agricultural Sciences, Department of Microbiology
Swedish University of Agricultural Sciences, Department of Chemistry
UKÄ Subject classification
Organic Chemistry
Food Science
Microbiology
Publication Identifiers
DOI: https://doi.org/10.1021/np800105e
URI (permanent link to this page)
https://res.slu.se/id/publ/18990