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Research article2008Peer reviewed

Chemically Triggered Biodelivery Using Metal-Organic Sol-Gel Synthesis

Kessler, Vadim G.; Seisenbaeva, Gulaim A.; Unell, Maria; Hakansson, Sebastian

Abstract

Living cells can be coated with continuous oxide shells prepared from modified titanium alkoxides (see picture). The shells efficiently isolate the encapsulated biomaterial from the surrounding medium. The resulting colloid media are highly biocompatible; subsequent release (biodelivery) of encapsulated cells or drugs is possible by dissolution of the titania nanoparticles

Keywords

biodelivery; drug delivery; metal alkoxides; sol-gel processes

Published in

Angewandte Chemie International Edition
2008, Volume: 47, number: 44, pages: 8506-8509
Publisher: WILEY-V C H VERLAG GMBH