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Research article2009Peer reviewedOpen access

Malignant acoustic schwannoma in a dog

Ottinger, Therese; Lindberg, Ronny; Ekman, Stina

Abstract

A malignant schwannoma of the right acoustic nerve of it dog is described. The neoplasm was found during necropsy of a 12-year-old, spayed, female Labrador Retriever that experienced a sudden onset of severe pain in the neck and upon opening the mouth. Concurrent mild hind limb ataxia also was present. The tumor had infiltrative growth, and the spindle-shaped neoplastic cells were arranged in sheets and concentric whorls. Immunohistochemical staining of the neoplastic spindle cells was positive for S-100 antigen, neuron-specific enolase, and glial fibrillary acidic protein.

Keywords

Acoustic nerve; dogs; glial fibrillary acidic protein; Labrador Retriever; malignant schwannoma; neuron-specific enolase; S-100

Published in

Journal of Veterinary Diagnostic Investigation
2009, Volume: 21, number: 1, pages: 129-132