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Conference paper2008Peer reviewed

Non-uniform 3D distance transform for anisotropic signal correction in confocal image volumes of skeletal muscle cell nuclei

Karlsson, Edlund Patrick; Lindblad, Joakim


Detailed description of the three dimensional organization of nuclei in confocal microscope image volumes of skeletal muscle fibers needs accurate identification of the nuclei centroids. We propose a model based method, applied as a weighted distance transform that take into consideration the diffuse, attenuated, anisotropic, and non-symmetric behavior of the nuclei signals, to provide a transformed image volume where the individual nuclei are better separated, and where the correct nuclei centroids are easily attained


Image processing; Morphological operations; Microscopy; Biological cells; Muscles

Published in

ISBN: 978-1-4244-2003-2


IEEE International Symposium on Biomedical Imaging: From Nano to Macro

      SLU Authors

    • Lindblad, Joakim

      • Centre for Image Analysis, Swedish University of Agricultural Sciences

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