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Research article2004Peer reviewed

Fluoroquinolone antibiotics in a hospital sewage line; Occurrence, distribution and impact on bacterial resistance

Jarnheimer PA, Ottoson J, Lindberg R, Stenstrom TA, Johansson M, Tysklind M, Winner MM, Olsen B


In hospital sewage lines, human faecal bacteria are exposed to antibiotics, posing a risk for selection of antibiotic resistant microorganisms. We constructed a system for continuous sampling in a hospital sewage fine that allowed us to study longitudinal establishment of bacteria, concentrations of antibiotics, and,selection of bacterial resistance in waste water, sediment and biofilm. The focus in this study was on fluoroquinolones, a Widely used group of antibiotics with increasing resistance problems. We found low levels of ciprofloxacin and ofloxacin in Waste water but high concentrations in sediment. Despite the high levels of fluoroquinolones bound to sediment, we did not find any development of resistance against fluoroquinolones in Enterobacteriacae spp. and faecal enterococci isolated from sediment

Published in

Scandinavian Journal of Infectious Diseases
2004, Volume: 36, number: 10, pages: 752-755

    UKÄ Subject classification

    Food Science
    Fish and Aquacultural Science
    Environmental Sciences related to Agriculture and Land-use

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