Fluoroquinolone antibiotics in a hospital sewage line; Occurrence, distribution and impact on bacterial resistance

Abstract

In hospital sewage lines, human faecal bacteria are exposed to antibiotics, posing a risk for selection of antibiotic resistant microorganisms. We constructed a system for continuous sampling in a hospital sewage fine that allowed us to study longitudinal establishment of bacteria, concentrations of antibiotics, and,selection of bacterial resistance in waste water, sediment and biofilm. The focus in this study was on fluoroquinolones, a Widely used group of antibiotics with increasing resistance problems. We found low levels of ciprofloxacin and ofloxacin in Waste water but high concentrations in sediment. Despite the high levels of fluoroquinolones bound to sediment, we did not find any development of resistance against fluoroquinolones in Enterobacteriacae spp. and faecal enterococci isolated from sediment

Published in

Scandinavian Journal of Infectious Diseases
2004, volume: 36, number: 10, pages: 752-755
Publisher: TAYLOR & FRANCIS AS

SLU Authors

• Ottoson, Jakob

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Food Science
Fish and Aquacultural Science
Environmental Sciences and Nature Conservation

Publication identifier

• DOI: https://doi.org/10.1080/00365540410021027

Permanent link to this page (URI)

https://res.slu.se/id/publ/21646