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Research article2009Peer reviewed

Interleukin-6 and high mobility group box protein-1 in synovial membranes and osteochondral fragments in equine osteoarthritis

Ley, Cecilia; Ekman, Stina; Ronéus, Bengt; Eloranta, M-L

Abstract

Cytokine production in synovial membranes (SM) and osteochondral fragments (OCF) may influence the development of equine osteoarthritis (OA). In this study, the presence of interleukin (IL)-6 and cytoplasmic and extraellular high mobility group box protein (HMGB)-1 in SM and osteochodnral tissue from healthy and diseased equine joints was investigated by immunohistochemistry

Keywords

IL-6; HMGB-1; Cytokines; Equine; Osetochondral fragment; Osteoarthritis

Published in

Research in Veterinary Science
2009, Volume: 86, number: 3, pages: 490-497 Publisher: Elsevier