Abstract

In many species reproduction and embryonic development have been shown to be sensitive to environmental contaminants. Understanding embryonic exposure to environmental contaminants is thus highly important. In this study concentrations of brominated flame retardants (BFRs) were measured in zebrafish eggs after parental exposure for 42 days via the diet. Zebrafish were exposed to two doses of eleven structurally-diverse BFRs. Eight BFRs were detected in the female zebrafish and maternal transfer to eggs was evident for all eight compounds. The highest concentrations in eggs were observed for hexabromo-cyclododecane (HBCD) and 2,4,4'-tribromodiphenyl ether (BDE 28), followed by 2,2',3,4,4',5',6-heptabromodiphenyl ether (BDE 183) and tetrabromobisphenol A 2,3-dibromopropyl ether (TBBPA DBPE). Five potential BFR metabolites were tentatively identified in female fish and maternal transfer was observed also for these compounds. The lipid adjusted concentrations in eggs were significantly higher than the concentrations in female fish for several of the BFRs. Further, the results showed a generally higher transfer in the lower exposure level and also indicated a dependency on the physico-chemical properties of the compounds. (c) 2008 Elsevier Ltd. All rights reserved.

Keywords

Maternal transfer; Dietary Exposure; Zebrafish; Egg; Brominated flame retardants

Published in

Chemosphere
2008, Volume: 73, number: 2, pages: 203-208
Publisher: PERGAMON-ELSEVIER SCIENCE LTD

SLU Authors

• Norman Haldén, Anna

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Norrgren, Leif

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Environmental Sciences related to Agriculture and Land-use


Publication identifier

DOI: https://doi.org/10.1016/j.chemosphere.2008.04.033

Permanent link to this page (URI)

https://res.slu.se/id/publ/27364