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Review article2009Peer reviewed

Endogenous and exogenous transplacental transmission of Neospora caninum - how the route of transmission impacts on epidemiology and control of disease

Williams, D. J. L.; Hartley, C. S.; Bjorkman, C.; Trees, A. J.

Abstract

Vertical transmission of the protozoan parasite, Neospora caninum is highly efficient and can take two forms - endogenous transplacental transmission resulting from activation of the quiescent bradyzoite stage during pregnancy or exogenous transplacental transmission resulting from ingestion of oocysts during pregnancy. Calves born carrying infection derived from either endogenous or exogenous transplacental transmission are capable of infecting their offspring when they start to breed. This review considers firstly the frequency with which exogenous and endogenous transmission occur, secondly the role of the immune response in controlling N. caninum infection and thirdly how the parasite persists in an immune-competent host and is re-activated during pregnancy.

Published in

Parasitology
2009, Volume: 136, number: 14, pages: 1895-1900

    UKÄ Subject classification

    Veterinary Science
    Animal and Dairy Science

    Publication identifier

    DOI: https://doi.org/10.1017/S0031182009990588

    Permanent link to this page (URI)

    https://res.slu.se/id/publ/27493