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Research article2009Peer reviewedOpen access

Scientific Opinion on Analytical sensitivity of approved TSE rapid tests

Androletti, Olivier; Budka, Herbert; Buncic, Sava; Collins, John D; Griffin, John; Hald, Tine; Havelaar, Arie H; Hope, James; Klein, Gunter; McLauchlin, James; Messens, Winy; Müller-Graf, Christine; Nguyen-The, Christophe; Nörrung, Birgit; Paixe, Luisa; Prieto, Maradona Miguel; Ricci, Antonia; Sofos, John; Threlfall, John; Vågsholm, Ivar;
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Abstract

The Community Reference Laboratory (CRL) for TSEs studied the analytical sensitivity for all the currently approved TSE rapid tests in order to produce robust analytical sensitivity data and evaluate each test against the same sample sets for the three main types of ruminant TSE: BSE, Classical scrapie and Atypical scrapie. This opinion provides a scientific evaluation of the CRL analytical sensitivity study, based on the requirements as set in the current EFSA protocols for the evaluation of TSE rapid post mortem tests. It is concluded that the CRL study findings provide valuable information in determining the continued suitability of tests currently used for TSE monitoring in the EU. Conclusions on the performance of the approved rapid tests within the CRL study are included. On these bases a number of tests cannot be recommended for use for the monitoring of BSE in cattle and TSE in small ruminants in the EU. Finally, the BIOHAZ Panel recommends that a similar study should be conducted with other types of TSE in cattle and small ruminants

Keywords

BSE; Classical scrapie; Atypical scrapie; analytical sensitivity; TSE rapid tests

Published in

EFSA Journal
2009, Volume: 7, number: 12, article number: 1436
Publisher: European Food Safety Authority (EFSA)

    UKÄ Subject classification

    Food Science
    Animal and Dairy Science
    Veterinary Science

    Publication identifier

    DOI: https://doi.org/10.2903/j.efsa.2009.1436

    Permanent link to this page (URI)

    https://res.slu.se/id/publ/27494