The SUR2 gene of Arabidopsis thaliana encodes the cytochrome P450CYP83B1, a modulator of auxin homeostasis

Abstract

Genetic screens have been performed to identify mutants with altered auxin homeostasis in Arabidopsis. A tagged allele of the auxin-overproducing mutant sur2 was identified within a transposon mutagenized population. The SUR2 gene was cloned and shown to encode the CYP83B1 protein, which belongs to the targe family of the P450-dependent monooxygenases. SUR2 expression is up-regulated in sur1 mutants and induced by exogenous auxin in the wild type. Analysis of indole3-acetic acid (IAA) synthesis and metabolism in sur2 plants indicates that the mutation causes a conditional increase in the pool size of IAA through up-regulation of IAA synthesis.

Keywords

metabolism

Published in

Proceedings of the National Academy of Sciences
2000, volume: 97, number: 26, pages: 14819-14824
Publisher: NATL ACAD SCIENCES

SLU Authors

• Kowalczyk, Mariusz

  • Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences
    

• Marchant, Alan

  • University of Nottingham

• Ljung, Karin

  • Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences
    

• Bhalerao, Rishikesh P.

  • Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences
    

• Sandberg, Göran

  • Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences
    

• Bellini, Catherine

  • National Institute of Agricultural Research (INRA)

UKÄ Subject classification

Biochemistry and Molecular Biology

Publication identifier

• DOI: https://doi.org/10.1073/pnas.260502697

Permanent link to this page (URI)

https://res.slu.se/id/publ/41662