Modification and cross-linking parameters in hyaluronic acid hydrogels-Definitions and analytical methods

Kenne, Lennart; Gohil, Suresh; Nilsson, Eva; Karlsson, Anders; Ericsson, David; Helander Kenne, Anne; Nord, Lars I.

doi:10.1016/j.carbpol.2012.08.066

Research article - Peer-reviewed, 2013

Modification and cross-linking parameters in hyaluronic acid hydrogels-Definitions and analytical methods

Kenne, Lennart; Gohil, Suresh; Nilsson, Eva; Karlsson, Anders; Ericsson, David; Helander Kenne, Anne; Nord, Lars I.

Abstract

The method, could be applicable to the major cross-linked HA hydrogels currently on the market, and is exemplified here by application to two HA hydrogels. The definitions and methods presented are important contributions in attempts to find relationships between MoD, DS and CrD to mechanical properties as well as to biocompatibility of HA hydrogels. (C) 2012 Elsevier Ltd. All rights reserved.

Keywords

Hyaluronan; Hydrogel; Degree of cross-linking; Effective cross-linker ratio; Degree of modification; Characterization; Determination

Published in

Carbohydrate Polymers
2013, volume: 91, number: 1, pages: 410-418
Publisher: ELSEVIER SCI LTD

Authors' information

Kenne, Lennart

Swedish University of Agricultural Sciences, Department of Chemistry

Gohil, Suresh

Swedish University of Agricultural Sciences, Department of Chemistry

Nilsson, Eva

Karlsson, Anders

Ericsson, David

Helander Kenne, Anne

Nord, Lars I.

UKÄ Subject classification

Analytical Chemistry

Publication Identifiers

DOI: https://doi.org/10.1016/j.carbpol.2012.08.066

URI (permanent link to this page)

https://res.slu.se/id/publ/41972