Moschou, Panagiotis Nikolaou
- Department of Plant Biology, Swedish University of Agricultural Sciences
Research article2012Peer reviewed
Separases: biochemistry and function
Moschou, Panagiotis Nikolaou; Bozhkov, Peter
Abstract
Tight regulation of cell cycle is of critical importance for eukaryotic biology and is achieved through a combined action of a large number of highly specialized proteins. Separases are evolutionarily conserved caspase-like proteases playing a crucial role in cell cycle regulation, as they execute sister chromatid separation at metaphase to anaphase transition. In contrast to extensively studied yeast and metazoan separases, very little is known about the role of separases in plant biology. Here we describe the molecular mechanisms of separase-mediated chromatid segregation in yeast and metazoan models, discuss new emerging but less-understood functions of separases and highlight major gaps in our knowledge about plant separases.
Published in
Physiologia Plantarum
2012, volume: 145, number: S1, pages: 67-76
Publisher: WILEY-BLACKWELL
SLU Authors
Bozhkov, Peter
- Department of Plant Biology, Swedish University of Agricultural Sciences
- Department of Plant Biology, Swedish University of Agricultural Sciences
UKÄ Subject classification
Cell Biology
Publication identifier
- DOI: https://doi.org/10.1111/j.1399-3054.2011.01550.x
Permanent link to this page (URI)
https://res.slu.se/id/publ/42333