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Patent, 2017

Protein

Howard, William; Watson, Alastair; Madsen, Jens; Johansson, Jan; Rising, Anna; Kronqvist, Nina; Nordling, Kerstin

Abstract

The present invention provides a fusion protein comprising: i) a solubility-enhancing moiety which is derived from the N-terminal (NT) fragment of a spider silk protein; and ii) a C-type lectin polypeptide. The present invention also provides a truncated SP-A polypeptide which lacks the N-terminal domain of full SP-A and is capable of trimerisation, and to the use of such a truncated SP-A polypeptide in treating or preventing a disease.

Published in


Application number: PCT/GB2016/054004
Patent number: WO2017109477A3
Application published date: 2017-06-29
Publication date: 2017-08-24

Authors' information

Howard, William
University of Southampton
Watson, Alastair
University of Southampton
Madsen, Jens
University of Southampton
Johansson, Jan
Swedish University of Agricultural Sciences, Department of Anatomy, Physiology and Biochemistry (AFB)
Swedish University of Agricultural Sciences, Department of Anatomy, Physiology and Biochemistry (AFB)
Kronqvist, Nina
Karolinska Institute
Nordling, Kerstin
Swedish University of Agricultural Sciences, Department of Anatomy, Physiology and Biochemistry (AFB)

UKÄ Subject classification

Biomedical Laboratory Science/Technology

URI (permanent link to this page)

https://res.slu.se/id/publ/42820