Abstract

The present invention provides a fusion protein comprising: i) a solubility-enhancing moiety which is derived from the N-terminal (NT) fragment of a spider silk protein; and ii) a C-type lectin polypeptide. The present invention also provides a truncated SP-A polypeptide which lacks the N-terminal domain of full SP-A and is capable of trimerisation, and to the use of such a truncated SP-A polypeptide in treating or preventing a disease.

Published in

Application number: PCT/GB2016/054004
Patent number: WO2017109477A3
Application published date: 2017-06-29
Publication date: 2017-08-24

SLU Authors

• Johansson, Jan

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Rising, Anna

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Nordling, Kerstin

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Biomedical Laboratory Science/Technology


More information

Assignees: UNIVERSITY OF SOUTHAMPTON [GB/GB], SPIBER TECHNOLOGIES AB [SE/SE]


Permanent link to this page (URI)

https://res.slu.se/id/publ/42820