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Review article2013Peer reviewed

Intervertebral disc degeneration in the dog. Part 1: Anatomy and physiology of the intervertebral disc and characteristics of intervertebral disc degeneration

Bergknut, Niklas; Smolders, Lucas A.; Grinwis, Guy C.M.; Hagman, Ragnvi; Lagerstedt, Anne-Sofie; Hazewinkel, Herman; Tryfonidou, Marianna A.; Meij, Björn P.


Intervertebral disc (IVD) degeneration is common in dogs and can give rise to a number of diseases, such as IVD herniation, cervical spondylomyelopathy, and degenerative lumbosacral stenosis. Although there have been many reports and reviews on the clinical aspects of canine IVD disease, few reports have discussed and reviewed the process of IVD degeneration. In this first part of a two-part review, the anatomy, physiology, histopathology, and biochemical and biomechanical characteristics of the healthy and degenerated IVD are described. In Part 2, the aspects of IVD degeneration in chondrodystrophic and non-chondrodystrophic dog breeds are discussed in depth


Intervertebral disc; Degeneration; Dog; Chondrodystrophic; Non-chondrodystrophic

Published in

Veterinary Journal
2013, Volume: 195, number: 3, pages: 282-291 Publisher: ELSEVIER SCI LTD